Citocoline (CDP Choline) Research

Characteristics

Supplies an important cellular building block essential to brain function, enhancing psychomotor speed, learning, focus, and recall. It demonstrates the ability to promote brain cell membrane integrity, neuronal repair, brain energy metabolism, and blood flow, and has been shown to reduce the risk of cognitive decline.*

Research

Citicoline: Neuroprotective Mechanisms in Cerebral Ischemia

 This study explores the neuroprotective mechanisms of citicoline in cerebral ischemia, highlighting its potential to reduce brain damage and improve recovery.

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Citicoline for Supporting Memory in Aging Humans

 This study found that citicoline supplementation improves memory function in older adults, suggesting its potential to reverse early age-related cognitive changes.

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Citicoline and Memory Function in Healthy Older Adults: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

 This clinical trial demonstrated that citicoline supplementation significantly improved memory function in healthy older adults with age-associated memory impairment.

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Citicoline: A Superior Form of Choline?

 This review discusses the potential superiority of citicoline as a form of choline, highlighting its bioavailability and cognitive benefits.

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Citicoline: A Novel Therapeutic Agent with Neuroprotective, Neuromodulatory, and Neuroregenerative Properties

 This review highlights the neuroprotective, neuromodulatory, and neuroregenerative properties of citicoline, showing its benefits in improving cognitive function and memory.

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Citicoline Enhances Frontal Lobe Bioenergetics as Measured by Phosphorus Magnetic Resonance Spectroscopy

 This study found that citicoline enhances frontal lobe bioenergetics, suggesting its potential to improve cognitive function.

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Chronic Citicoline Increases Phosphodiesters in the Brains of Healthy Older Subjects: An In Vivo Phosphorus Magnetic Resonance Spectroscopy Study

 This study found that chronic citicoline supplementation increases brain phosphodiesters, suggesting its potential to enhance brain health in older adults.

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Effect of Oral CDP-Choline on Plasma Choline and Uridine Levels in Humans

 This study found that oral CDP-choline increases plasma choline and uridine levels, supporting its role in cognitive enhancement.

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Citicoline Decreases Phospholipase A2 Stimulation and Hydroxyl Radical Generation in Transient Cerebral Ischemia

 This study found that citicoline reduces phospholipase A2 stimulation and hydroxyl radical generation, suggesting its neuroprotective effects in cerebral ischemia.

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Citicoline: Pharmacological and Clinical Review

 This review provides a comprehensive overview of the pharmacological and clinical benefits of citicoline, highlighting its neuroprotective and cognitive-enhancing properties.

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Citicoline and Memory Function in Healthy Older Adults

 This clinical trial demonstrated that citicoline supplementation significantly improved memory function in healthy older adults with age-associated memory impairment.

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