Lion's Mane Research

Characteristics

The only mushroom with nootropic properties. Shown to stimulate synthesis of nerve growth factor (NGF), promoting brain regeneration and repair, memory, mental clarity, and recovery from neuropathy and nerve damage. Our formula contains the highest potency and purest extraction available. *

Research

Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: a double-blind placebo-controlled clinical trial

 A double-blind, placebo-controlled trial examining the effects of oral Hericium erinaceus on mild cognitive impairment using the Revised Hasegawa Dementia Scale.

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Improvement of cognitive functions by oral intake of Hericium erinaceus

 A randomized, double-blind, placebo-controlled study evaluating cognitive function improvements after 12 weeks of Hericium erinaceus supplementation.

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Erinacine S, a Rare Sesterterpene from the Mycelia of Hericium erinaceus

Isolation and structural elucidation of the rare sesterterpene erinacine S from H. erinaceus mycelia.

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Nerve growth factor-inducing activity of Hericium erinaceus in 1321N1 human astrocytoma cells

 This study found H. erinaceus induced nerve growth factor synthesis in human astrocytoma cells.

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The Cyanthin Diterpenoid and Sesterterpene Constituents of Hericium erinaceus Mycelium Ameliorate Alzheimer's Disease-Related Pathologies in APP/PS1 Transgenic Mice

 This study found cyanthin diterpenoids and sesterterpenes from H. erinaceus mycelium reduced Alzheimer's pathologies in transgenic mice.

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Prevention of Early Alzheimer's Disease by Erinacine A-Enriched Hericium erinaceus Mycelia Pilot Double-Blind Placebo-Controlled Study

 An erinacine A-enriched H. erinaceus supplement improved cognitive scores in patients with mild Alzheimer's disease.

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The Acute and Chronic Effects of Lion’s Mane Mushroom Supplementation on Cognitive Function, Stress and Mood in Young Adults: A Double-Blind, Parallel Groups, Pilot Study

 This study found that Lion’s Mane improved speed of performance and reduced subjective stress in healthy young adults.

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Neurotrophic properties of the Lion's mane medicinal mushroom

 This study explored the neuroprotective effects of Lion’s Mane, showing its potential to enhance neurite outgrowth and protect against oxidative stress.

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Therapeutic Potential of Hericium erinaceus for Depressive Disorder

 This review highlights the potential of Lion’s Mane in treating depressive disorders, emphasizing its neuroprotective and anti-inflammatory properties.

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Neurological Activity of Lion's Mane (Hericium erinaceus)

 This review explores the neuroprotective and neuroregenerative properties of Lion’s Mane, suggesting its potential for treating Alzheimer’s and Parkinson’s diseases.

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Exploring the Science Behind Lion's Mane Mushroom

 This article discusses the cognitive and mood-enhancing effects of Lion’s Mane, based on recent research findings.

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Lion’s Mane Mushroom, Hericium erinaceus (Bull.: Fr.) Pers. Suppresses H2O2-Induced Oxidative Damage and LPS-Induced Inflammation in HT22 Hippocampal Neurons and BV2 Microglia

 This study found that Lion’s Mane suppresses oxidative damage and inflammation in hippocampal neurons and microglia.

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Therapeutic Potential of Hericium erinaceus for Depressive Disorder

 This study highlights the potential of Lion’s Mane in treating depressive disorders, emphasizing its neuroprotective and anti-inflammatory properties.

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